In the News

July 28, 2014 — Hepatocellular carcinoma (HCC) — the most common form of liver cancer — is the third leading cause of cancer-related death in the world, yet there are few effective therapies and virtually no predictive markers based on a molecular understanding of the disease.

To increase current knowledge of HCC genetics, scientists at the Children’s Medical Center Research Institute at UT Southwestern have generated efficient and physiologic liver cancer mouse models with in vivo use of a powerful genome-engineering tool known as Transcription Activator-Like Effector Nucleases, or TALENs.

Read the study published in Cancer Research.

Nov. 7, 2013 — Two groups of scientists at the Children’s Medical Center Research Institute at UT Southwestern have made complementary discoveries that break new ground on efforts to turn back the body’s clock on cellular activity, paving the way for a better understanding of stem cells, tissue growth and regeneration.

April 2, 2013 — Ralph DeBerardinis, M.D., Ph.D., and Hao Zhu, M.D., are the first two faculty members recruited to join Sean Morrison, Ph.D., at Children’s Medical Center Research Institute at UT Southwestern (CRI). Dr. DeBerardinis, whose lab focuses on cancer and metabolism, and Dr. Zhu, whose lab focuses on liver cancer, recently discussed their reasons for joining CRI and what each hopes to achieve through their research in the coming years. Read the Q&A.