Selected Agathocleous Lab Publications


Agathocleous, M., Meecham, C.E., Burgess, R.J., Piskounova, E., Zhao, Z., Crane, G.M., Cowin, B.L., Bruner, E., Murphy, M.M., Chen, W., Spangrude, G.J., Hu, Z., DeBerardinis, R.J., and Morrison, S.J. (2017). Ascorbate regulates haematopoietic stem cell function and leukaemogenesis. Nature 549, 476-481. (PubMed)


Piskounova, E., Agathocleous, M., Murphy, M.M., Hu, Z., Mann, S., Zhao, Z., Leitch, A.M., Johnson, T.M., DeBerardinis, R.J., and Morrison, S.J. (2015). Oxidative stress inhibits distant metastasis by human melanoma cells. Nature 527, 186-191. (PubMed)


Burgess, R.J.*, Agathocleous, M.*, and Morrison, S.J. (2014). Metabolic regulation of stem cell function. J Intern Med 276, 12-24. *co-first authors (PubMed)

Love, N.K., Keshavan, N., Lewis, R., Harris, W.A., and Agathocleous, M. (2014). A nutrient-sensitive restriction point is active during retinal progenitor cell differentiation. Development 141, 697-706. (PubMed)


Agathocleous, M.*, and Harris, W.A. (2013). Metabolism in physiological cell proliferation and differentiation. Trends Cell Biol 23, 484-492. *corresponding author (PubMed)


Agathocleous, M., Love, N.K., Randlett, O., Harris, J.J., Liu, J., Murray, A.J., and Harris, W.A. (2012). Metabolic differentiation in the embryonic retina. Nat Cell Biol 14, 859-864. (PubMed)


Agathocleous, M., Iordanova, I., Willardsen, M.I., Xue, X.Y., Vetter, M.L., Harris, W.A., and Moore, K.B. (2009). A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development 136, 3289-3299. (PubMed)

Agathocleous, M., and Harris, W.A. (2009). From progenitors to differentiated cells in the vertebrate retina. Annu Rev Cell Dev Biol 25, 45-69. (PubMed)


Agathocleous, M., Locker, M., Harris, W.A., and Perron, M. (2007). A general role of hedgehog in the regulation of proliferation. Cell Cycle 6, 156-159. (PubMed)


Agathocleous, M., Harris, W.A.: Cell determination (book chapter) in Retinal Development, Cambridge University Press (2006).

Locker, M.*, Agathocleous, M.*, Amato, M.A., Parain, K., Harris, W.A., and Perron, M. (2006). Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors. Genes Dev 20, 3036-3048. *co-first authors (PubMed)