Selected Agathocleous Lab Publications


Jun, S., Mahesula, S., Mathews, T.P., Martin-Sandoval, M.S., Zhao, Z., Piskounova, E., and Agathocleous, M.  (2021). The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage. Cell Met 33, 1777-1792. (PubMed)


Agathocleous, M., Meecham, C.E., Burgess, R.J., Piskounova, E., Zhao, Z., Crane, G.M., Cowin, B.L., Bruner, E., Murphy, M.M., Chen, W., Spangrude, G.J., Hu, Z., DeBerardinis, R.J., and Morrison, S.J. (2017). Ascorbate regulates haematopoietic stem cell function and leukaemogenesis. Nature 549, 476-481. (PubMed)


Piskounova, E., Agathocleous, M., Murphy, M.M., Hu, Z., Mann, S., Zhao, Z., Leitch, A.M., Johnson, T.M., DeBerardinis, R.J., and Morrison, S.J. (2015). Oxidative stress inhibits distant metastasis by human melanoma cells. Nature 527, 186-191. (PubMed)


Burgess, R.J.*, Agathocleous, M.*, and Morrison, S.J. (2014). Metabolic regulation of stem cell function. J Intern Med 276, 12-24. *co-first authors (PubMed)

Love, N.K., Keshavan, N., Lewis, R., Harris, W.A., and Agathocleous, M. (2014). A nutrient-sensitive restriction point is active during retinal progenitor cell differentiation. Development 141, 697-706. (PubMed)


Agathocleous, M.*, and Harris, W.A. (2013). Metabolism in physiological cell proliferation and differentiation. Trends Cell Biol 23, 484-492. *corresponding author (PubMed)


Agathocleous, M., Love, N.K., Randlett, O., Harris, J.J., Liu, J., Murray, A.J., and Harris, W.A. (2012). Metabolic differentiation in the embryonic retina. Nat Cell Biol 14, 859-864. (PubMed)


Agathocleous, M., Iordanova, I., Willardsen, M.I., Xue, X.Y., Vetter, M.L., Harris, W.A., and Moore, K.B. (2009). A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development 136, 3289-3299. (PubMed)

Agathocleous, M., and Harris, W.A. (2009). From progenitors to differentiated cells in the vertebrate retina. Annu Rev Cell Dev Biol 25, 45-69. (PubMed)


Agathocleous, M., Locker, M., Harris, W.A., and Perron, M. (2007). A general role of hedgehog in the regulation of proliferation. Cell Cycle 6, 156-159. (PubMed)


Agathocleous, M., Harris, W.A.: Cell determination (book chapter) in Retinal Development, Cambridge University Press (2006).

Locker, M.*, Agathocleous, M.*, Amato, M.A., Parain, K., Harris, W.A., and Perron, M. (2006). Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors. Genes Dev 20, 3036-3048. *co-first authors (PubMed)