Timeline Stories Archives | Page 2 of 4 | Children's Research Institute

July 27, 2020

Katie Regan

Stem cells discovered to take up unusually high levels of vitamin C, which regulates their function and suppresses the development of leukemia. These findings have implications for older patients with a common precancerous condition known as clonal hematopoiesis.

August 21, 2017 Stem cells discovered to take up unusually high levels of vitamin C, which regulates their function and..Read More

July 27, 2020

Katie Regan

An aggressive subset of lung cancer found to rely on a previously unknown mechanism for making DNA. These findings could result in new ways to treat lung cancer, the leading cause of cancer-related deaths worldwide.

June 20, 2017 An aggressive subset of lung cancer found to rely on a previously unknown mechanism for making DNA…Read More

July 27, 2020

Katie Regan

A new pathway that regulates mitochondrial function during blood cell production discovered. This discovery contributes to our understanding of the hematologic defects associated with mitochondrial diseases and aging.

May 24. 2017 A new pathway that regulates mitochondrial function during blood cell production discovered. This discovery contributes to our..Read More

July 27, 2020

Katie Regan

New bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has the potential to promote bone regeneration, discovered.

December 13, 2016 New bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has the potential to promote..Read More

July 27, 2020

Katie Regan

Researchers discovered a metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells, particularly the oxidative stress that limits cancer progression.

April 7, 2016 Researchers discovered a metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal..Read More

July 27, 2020

Katie Regan

Diet found to determine the balance between fat formation and bone formation in adult bone marrow. This settles a long-standing controversy and could have implications for treating osteoporosis.

March 29, 2016 Diet found to determine the balance between fat formation and bone formation in adult bone marrow. This..Read More

July 27, 2020

Katie Regan

Inactivating Arid1a, a gene associated with some human cancers, promotes liver regeneration. This study opens up new areas of investigation related to ways of rejuvenating tissues without increasing cancer risk.

March 25, 2016 Inactivating Arid1a, a gene associated with some human cancers, promotes liver regeneration. This study opens up new..Read More

July 27, 2020

Katie Regan

New method for studying metabolism in tumors within patients developed, overturning long-standing perceptions about cancer metabolism that were based on studies of cancer cells in laboratory dishes. These discoveries could lead to new ways of diagnosing and treating cancer.

February 4, 2016 New method for studying metabolism in tumors within patients developed, overturning long-standing perceptions about cancer metabolism that..Read More

July 27, 2020

Katie Regan

Researchers pioneer technologies to understand DNA sequences that regulate the ability of genes to be turned on and off during blood cell development. These discoveries pave the way to discover new regulatory DNA sequences that govern the production of blood cells and leukemia development.

January 11, 2016 Researchers pioneer technologies to understand DNA sequences that regulate the ability of genes to be turned on..Read More

July 27, 2020

Katie Regan

Researchers identified a secondary, emergency blood-formation system in the spleen. With this new information, therapies could be developed to enhance blood formation following chemotherapy or bone-marrow transplantation to accelerate recovery.

November 16, 2015 Researchers identified a secondary, emergency blood-formation system in the spleen. With this new information, therapies could be..Read More

Stem cells discovered to take up unusually high levels of vitamin C, which regulates their function and suppresses the development of leukemia. These findings have implications for older patients with a common precancerous condition known as clonal hematopoiesis.

An aggressive subset of lung cancer found to rely on a previously unknown mechanism for making DNA. These findings could result in new ways to treat lung cancer, the leading cause of cancer-related deaths worldwide.

A new pathway that regulates mitochondrial function during blood cell production discovered. This discovery contributes to our understanding of the hematologic defects associated with mitochondrial diseases and aging.

New bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has the potential to promote bone regeneration, discovered.

Researchers discovered a metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells, particularly the oxidative stress that limits cancer progression.

Diet found to determine the balance between fat formation and bone formation in adult bone marrow. This settles a long-standing controversy and could have implications for treating osteoporosis.

Inactivating Arid1a, a gene associated with some human cancers, promotes liver regeneration. This study opens up new areas of investigation related to ways of rejuvenating tissues without increasing cancer risk.

New method for studying metabolism in tumors within patients developed, overturning long-standing perceptions about cancer metabolism that were based on studies of cancer cells in laboratory dishes. These discoveries could lead to new ways of diagnosing and treating cancer.

Researchers pioneer technologies to understand DNA sequences that regulate the ability of genes to be turned on and off during blood cell development. These discoveries pave the way to discover new regulatory DNA sequences that govern the production of blood cells and leukemia development.

Researchers identified a secondary, emergency blood-formation system in the spleen. With this new information, therapies could be developed to enhance blood formation following chemotherapy or bone-marrow transplantation to accelerate recovery.

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