Researchers in the Agathocleous lab are studying how metabolites impact the stem cells genome and how the metabolism of cancer cells, and normal stem cells that give rise to cancers, compare.
The DeBerardinis lab is interested in the role of altered metabolic states in human diseases, particularly pediatric inborn errors of metabolism and cancer.
The Garcia-Bermudez lab aims to understand the role of metabolic adaptive mechanisms in cancer progression.
The Hoxhaj lab is interested in studying the molecular mechanisms that control cellular metabolism, particularly in cancer.
The McBrayer Lab seeks to discover metabolic mechanisms that promote brain tumor development and develop strategies to exploit altered metabolism for cancer therapy.
Research in the Mishra lab is focused on mapping how the mitochondria are embedded into normal cellular function.
The Morrison Lab studies mechanisms that regulate stem cell function in adult tissues and the ways in which those mechanisms get hijacked by cancer cells to enable tumor formation.
The Ohlstein lab is interested in understanding the mechanisms that guide normal and abnormal tissue functions, particularly in gastrointestinal organs such as the small and large intestines and stomach.
The Wu lab studies the molecular function and molecular basis of extrachromosomal DNA (ecDNA) in human cancer, including its replication, transcription, and repair.
The Xu lab focuses on blood cell development and how abnormalities can cause cancers such as childhood leukemia.
The Zhu laboratory is interested in understanding the relationship between injury, regeneration, and cancer.