News

December 23, 2025

Loss of vitamin C synthesis protects animals from schistosomiasis

Agathocleous Lab, collaborators discover vitamin C deficiency can benefit animals by depriving vitamin from parasitic worms …

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…

Metabolism

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

December 23, 2025

Loss of vitamin C synthesis protects animals from schistosomiasis

Agathocleous Lab, collaborators discover vitamin C deficiency can benefit animals by depriving vitamin from parasitic worms …

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help mutated cells …

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein NUDT5 is …

Metabolism

July 30, 2025

DeBerardinis Lab discovers first human peroxin in 20 years

CRI researchers, international colleagues identify PEX39, which facilitates peroxisomal protein import PEX39 is the first new …

Metabolism

June 11, 2025

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant protection from …

Cancer Biology

April 29, 2025

Hoxhaj Lab discovers how mitochondria use NADPH to fuel fatty acid synthesis, lipoylation

Mitochondrial NADPH — a metabolite and essential electron donor — drives mitochondrial fatty acid synthesis (mtFAS) …

Metabolism

March 12, 2025

DeBerardinis, Zhang find crucial metabolic pathway targeted by drug creates key vulnerability in cancer cells

Metabolism

February 19, 2025

DeBerardinis Lab finds high glucose contribution to tricarboxylic acid cycle involved in predicting cancer spread

DALLAS – Feb. 19, 2025 – In localized non-small cell lung cancer (NSCLC), a tumor’s ability …

Cancer Biology, Metabolism

January 28, 2025

DeBerardinis Lab featured in UTSW’s “Science in 60+: Renal Revelations”

January 24, 2025

Scientists unveil high-resolution human NAD kinase structure, key cancer metabolism regulator

Researchers at Children’s Medical Center Research Institute at UT Southwestern (CRI) and the Centre de Biologie …

December 30, 2024

Morrison Lab links hematopoietic cell transplant deaths to beta-blocker use

New CRI research shows nerve signaling needed for bone marrow regeneration may be impaired by medication …

Regenerative Medicine

December 20, 2024

Morrison Lab finds blood-forming stem cells process fatty acids differently as they age, with high-fat diet

New research from Children’s Medical Center Research Institute at UT Southwestern (CRI), out today in Cell …

Inside CRI Newsletter

Stay up-to-date with our latest discoveries and news by subscribing to our quarterly email newsletter.

Name

First Name Last Name

CAPTCHA

News

Loss of vitamin C synthesis protects animals from schistosomiasis

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

Category

Loss of vitamin C synthesis protects animals from schistosomiasis

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

DeBerardinis Lab discovers first human peroxin in 20 years

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

Hoxhaj Lab discovers how mitochondria use NADPH to fuel fatty acid synthesis, lipoylation

DeBerardinis, Zhang find crucial metabolic pathway targeted by drug creates key vulnerability in cancer cells

DeBerardinis Lab finds high glucose contribution to tricarboxylic acid cycle involved in predicting cancer spread

DeBerardinis Lab featured in UTSW’s “Science in 60+: Renal Revelations”

Scientists unveil high-resolution human NAD kinase structure, key cancer metabolism regulator

Morrison Lab links hematopoietic cell transplant deaths to beta-blocker use

Morrison Lab finds blood-forming stem cells process fatty acids differently as they age, with high-fat diet

Inside CRI Newsletter

About

Research

Shared Facilities

Training

News