Category: Discovery

Cancer Biology

May 19, 2026

Human cells can exchange genomic DNA that alters cell behavior

Children’s Research Institute scientists discover that DNA transferred between cells can be inherited, remain…

Cancer Biology, Regenerative Medicine

November 6, 2025

Location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…

Metabolism

November 6, 2025

Protein regulating balance between purine nucleotide production pathways discovered

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

Cancer Biology

June 11, 2025

Unique pathway tumors use to acquire antioxidant lipids uncovered

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant…

Regenerative Medicine

December 30, 2024

Hematopoietic cell transplant deaths linked to beta-blocker use

New CRI research shows nerve signaling needed for bone marrow regeneration may be impaired…

Regenerative Medicine

October 24, 2024

Ancient viral DNA activates blood cell production during pregnancy, after bleeding

Study published in Science shows humans co-opted retrotransposons to avoid anemia during pregnancy DALLAS…

Cancer Biology, Metabolism

August 14, 2024

Kidney cancers rely on mitochondrial metabolism to metastasize

DeBerardinis Lab researchers collaborated with UTSW surgeons to trace pathways used in kidney cancers…

Cancer Biology, Metabolism

July 11, 2024

Tumor growth fueled by nucleotide salvage

Hoxhaj Lab measures purine pathways across tissues and tumors, revealing crucial role of salvage…

Metabolism, Regenerative Medicine

June 13, 2024

Metabolic inflexibility keeps damage at bay during liver regeneration

Mishra Lab pinpoints PDK4 enzyme that starves cells with mitochondrial damage (NEWS RELEASE) Liver…

Cancer Biology

May 1, 2024

Small cell lung cancer acquires cross-resistance due to extrachromosomal DNA amplification of MYC paralogs

Summary: Small cell lung cancer (SCLC) presents as a highly chemosensitive malignancy but acquires…

Category: Discovery

Human cells can exchange genomic DNA that alters cell behavior

Location matters for liver cancer’s origins

Protein regulating balance between purine nucleotide production pathways discovered

Unique pathway tumors use to acquire antioxidant lipids uncovered

Hematopoietic cell transplant deaths linked to beta-blocker use

Ancient viral DNA activates blood cell production during pregnancy, after bleeding

Kidney cancers rely on mitochondrial metabolism to metastasize

Tumor growth fueled by nucleotide salvage

Metabolic inflexibility keeps damage at bay during liver regeneration

Small cell lung cancer acquires cross-resistance due to extrachromosomal DNA amplification of MYC paralogs

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