Dr. Jian Xu, Assistant Professor at CRI and UT Southwestern, and Dr. Kathryn Dickerson, Assistant Instructor in Pediatrics at UT Southwestern, have been awarded a $100K grant from Leukemia Texas to study acute myeloid leukemia (AML), which accounts for 90% of all acute leukemias in adults and 15-20% of those in children.
Drs. Xu and Dickerson will use the grant to develop a “first-in-kind” approach, using experimental and computational technologies to comprehensively identify pathogenic genetic abnormalities as new drivers of AML development. This study will help translate findings from cancer genetic studies to mechanism-based therapies for blood cancers, which can be easily extended to other types of human cancers.