Life at CRI

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Life At CRI

Life At The Institute: Wenyue Liu

August 17, 2022 By Katie Regan | No Comments

In the Wu lab at CRI, postdoctoral fellow Wenyue Liu, Ph.D., is working to understand the cancer-promoting functions of extrachromosomal DNA (ecDNA). Deciphering the functions of ecDNA will help scientists...

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Life At CRI

Life At The Institute: Milan Savani

May 17, 2022 By Katie Regan | No Comments

Milan Savani is an M.D./Ph.D. student in the Medical Scientist Training Program (MSTP) at UT Southwestern. In the McBrayer lab at CRI, he studies how brain cancer cells use nutrients...

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Life At CRI

Life At The Institute: Yafeng Li, Ph.D.

May 10, 2022 By Katie Regan | No Comments

Yafeng Li, Ph.D., is a postdoctoral fellow in the Agathocleous lab at CRI. As a trained analytical chemist specialized in mass spectrometry, she studies how metabolites, the small molecules of...

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Life At CRI

Life At The Institute: Chelsee Greer, D.O.

April 21, 2022 By Katie Regan | No Comments

Chelsee Greer, D.O., is a pediatric hematology/oncology fellow at UT Southwestern where she splits her time between seeing patients and working in the Xu lab at CRI. Her work in...

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Life At CRI

Life At The Institute: Alex Sternisha

January 19, 2022 By Katie Regan | No Comments

Alex Sternisha is an M.D./Ph.D. student in the Medical Scientist Training Program (MSTP) at UT Southwestern. In the McBrayer lab, he studies how small molecules that are produced and consumed...

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Life At CRI

Life At The Institute: Spencer Shelton

August 2, 2021 By Katie Regan | No Comments

Spencer Shelton is a fourth-year graduate student in the Mishra lab and a National Science Foundation Graduate Research Fellow. He is studying the role of mitochondrial DNA variations in metastatic...

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Life At CRI

Life At The Institute: Stefano Comazzetto, Ph.D.

June 23, 2021 By Katie Regan | No Comments

Stefano Comazzetto, Ph.D., is a European Molecular Biology Organization (EMBO) fellow and a postdoctoral researcher in the Morrison lab. At CRI, he is studying blood-forming stem cells and how metabolites...

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Life At CRI

Life At The Institute: Andrew Chung

June 9, 2021 By Katie Regan | No Comments

Andrew Chung is an M.D./Ph.D. student in the Medical Scientist Training Program (MSTP) at UT Southwestern. In the Zhu lab, Andrew is studying the influence of liver metabolic zonation on...

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Life At CRI

Life at the Institute: Aparna Rao, MBBS, Ph.D.

May 10, 2021 By Katie Regan | No Comments

Aparna Rao, MBBS, Ph.D., worked as a postdoctoral fellow in the DeBerardinis lab for three years studying melanoma metabolism. She recently returned to Australia to finish her training as a...

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Life At CRI

Life at the Institute: Zixi Wang, Ph.D.

March 18, 2021 By Katie Regan | No Comments

Zixi Wang, Ph.D., is a postdoctoral fellow in the Zhu lab and an assistant instructor of pediatrics at UT Southwestern. He is studying how mutations in SWI/SNF chromatin remodeling complexes...

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Life At CRI

Life at the Institute: Le Qi

December 8, 2020 By Katie Regan | No Comments

Le Qi is a graduate student in the Morrison lab and a Howard Hughes Medical Institute International Predoctoral Student Research Fellow. At CRI, he is studying the metabolism of blood-forming...

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Life At CRI

Life at the Institute: Faith Zhang, M.D., Ph.D.

November 4, 2020 By Katie Regan | No Comments

Faith Zhang, M.D., Ph.D., is a radiation oncology clinical fellow in the DeBerardinis lab. At CRI, she works to uncover metabolic targets to improve the effectiveness of radiotherapy. Resistance to...

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Life At CRI

Life at the Institute: Giovanni Botten

September 29, 2020 By Katie Regan | No Comments

Giovanni Botten is a M.D./Ph.D. student in the Medical Scientist Training Program at UT Southwestern. As part of the Xu lab at CRI he is studying how large-scale changes in...

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Life At CRI

Life at the Institute: Nicholas Lesner

August 24, 2020 By Katie Regan | No Comments

Nicholas Lesner is a third-year graduate student in the Mishra lab and a Ruth L. Kirschstein National Service Award Individual Predoctoral Fellowship awardee. At CRI, he is studying how mutations...

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Life At CRI

Life at the Institute: Xun Wang, Ph.D.

July 28, 2020 By Katie Regan | No Comments

Xun Wang, Ph.D. is a postdoctoral researcher in the Mishra lab who is studying how changes in mitochondria influences muscle stem cells maintenance and repair. His work will help us...

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Life At CRI

Life at the Institute: Austin Moore

July 14, 2020 By Katie Regan | No Comments

Austin Moore is an M.D./Ph.D. student in the Medical Scientist Training Program (MSTP) at UT Southwestern and previously held a Medical Research Fellowship from the Howard Hughes Medical Institute (HHMI)....

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Life At CRI

Life at the Institute: Zhimin Gu, Ph.D.

June 30, 2020 By Katie Regan | No Comments

Zhimin Gu is a postdoctoral fellow in the Xu lab and a member of the Moody Medical Research Institute. At CRI, he is working to discover metabolic vulnerabilities in acute...

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Life At CRI

Life at the Institute: Cemre Celen

June 8, 2020 By Katie Regan | No Comments

Cemre Celen is a sixth year graduate student in the Zhu lab. At CRI, she studies the regeneration of β-cells which are the insulin producing cells in the pancreas lost...

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Life At CRI

Life at the Institute: Jennifer Gill, M.D., Ph.D.

May 21, 2020 By Katie Regan | No Comments

Jennifer Gill, M.D., Ph.D., is a scientist at CRI and a practicing dermatologist. As a researcher in the Morrison lab, she studies how melanoma spreads from the skin to other...

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Metabolism researcher Dr. Ashley Solmonson sitting at lab bench smiling

Life At CRI

Life at the Institute: Ashley Solmonson, Ph.D.

May 5, 2020 By Katie Regan | No Comments

Ashley Solmonson, Ph.D., is a Ruth L. Kirschstein National Research Service Award (NRSA) Fellow in the DeBerardinis lab. At CRI, she studies how metabolism supports fetal growth during pregnancy and...

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Life At CRI

Life at the Institute: Elise Jeffrey, Ph.D.

April 22, 2020 By Katie Regan | No Comments

Elise Jeffrey, Ph.D., is a Damon Runyon Foundation Fellow in the Morrison lab. At CRI, Elise is studying blood stem cells and their environment to find new therapies for patients...

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Grad student Divya Bezwada taking cells our of incubator

Life At CRI

Life At The Institute: Divya Bezwada

March 10, 2020 By Katie Regan | No Comments

Graduate student Divya Bezwada is a Ruth L. Kirschstein NRSA Predoctoral Fellow at Children’s Medical Center Research Institute (CRI). In the DeBerardinis lab she works as part of an interdisciplinary...

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Life At CRI

Life At The Institute: Brandon Faubert, Ph.D.

February 25, 2020 By Katie Regan | No Comments

Brandon Faubert, Ph.D., is a Canadian Institutes of Health Research Fellow at Children’s Medical Center Research Institute (CRI) at UT Southwestern. He works in the DeBerardinis lab studying tumor metabolism....

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Life At CRI

Life At The Institute: Sojeong Jun

February 13, 2020 By Katie Regan | No Comments

Sojeong Jun is a graduate student at CRI. She is part of the Agathocleous lab where she is working to discover new treatment options for patients with leukemia. What are...

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Life At CRI

Life at the Institute: McKenzie Patrick

January 21, 2020 By Katie Regan | No Comments

McKenzie Patrick is a graduate student at the Children’s Medical Center Research Institute (CRI). She is a part of Dr. Jian Xu’s lab where she is working to better understand...

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Life At CRI

Life At The Institute: Wen Gu, Ph.D.

January 7, 2020 By Katie Regan | No Comments

Wen Gu is a postdoctoral researcher at the Children’s Medical Center Research Institute (CRI). He works in the lab of Dr. Ralph DeBerardinis as part of the Genetic and Metabolic...

The Children’s Research Institute is home to over 150 researchers from all over the world working to answer fundamental scientific questions. Researchers at the CRI receive outstanding training, support and scientific guidance.

Quick Facts Since Our Founding

Founded in

2011

Primary Faculty

12

HHMI Investigators

2

Extramural Funding

$189M

Senior Author Publications

123

NIH R01 Grants

23

CRI Statistics

Publications in High-Impact Journals*

Recent Publications

Morrison Lab: Ascorbate regulates haematopoietic stem cell function and leukaemogenesis. Nature

DeBerardinis Lab: Lactate Metabolism in Human Lung Tumors. Cell

Zhu Lab: Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease. Cell

Xu Lab: In situ capture of chromatin interactions by biotinylated dCas9. Cell

Mishra Lab: α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells. Metab Eng

Extramural Funding

CRI Postdoctoral Fellowship Sponsors

Why CRI?

Graduate students, postdocs and CRI staff share what it means to work at CRI.

Life at the Institute

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Founded
in

NIH R01
Grants