News

December 23, 2025

Loss of vitamin C synthesis protects animals from schistosomiasis

Agathocleous Lab, collaborators discover vitamin C deficiency can benefit animals by depriving vitamin from parasitic worms …

Regenerative Medicine

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…

Metabolism

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

November 27, 2013

Researchers unravel mystery of how leukemia-causing mutations enable pre-leukemic stem cells to outperform their healthy counterparts

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI), the University of California …

November 27, 2013

Nature: Stem cells – Dual response to Ras mutation

When a stem cell divides, it can either produce differentiated cells or self-renew to produce more …

November 11, 2013

Dallas Observer: UT Southwestern researcher identifies gene that tricks the body into healing like a fetus

Somewhere along the way, the purifying imperatives of evolution decided to dial back our bodies’ ability …

November 7, 2013

Nature: Fountain-of-youth gene unleashes healing power

Mice that had been genetically engineered to develop tumours failed to do so. Instead, the animals …

November 7, 2013

Cellular regeneration discoveries seek to turn back the body’s clock

Two groups of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have …

October 24, 2013

CRI researcher identifies new lung cancer therapeutic targets

A group of researchers including Ralph DeBerardinis, M.D., Ph.D., Director of the Genetic and Metabolic Disease …

September 23, 2013

Q&A with Woo-Ping Ge, Ph.D.

Children’s Research Institute at UT Southwestern (CRI) has recruited a new faculty member, Woo-Ping Ge, Ph.D. …

September 19, 2013

Sean Morrison and Corbin Meacham evaluate implications of new cancer stem cell data

Previously published research has suggested that the properties of cancer stem cells can explain a variety …

September 3, 2013

CRI researchers review metabolic functions of glutamine

Glutamine is an abundant and highly versatile nutrient whose metabolism has implications for tumor cell biology, …

August 26, 2013

Sean Morrison, Ph.D., discusses stem cell research at Science Café

I wear several different hats. I serve as director of the Children’s Medical Center Research Institute …

August 1, 2013

CRI researcher finds glucose connection to blood vessel formation

An international team of researchers including Ralph DeBerardinis, M.D., Ph.D., Director of the Genetic and Metabolic …

July 25, 2013

CRI researcher finds connection between excess fumarate and cancer

Researchers including Ralph DeBerardinis, M.D., Ph.D., Director of the Genetic and Metabolic Disease Program at the …

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News

Loss of vitamin C synthesis protects animals from schistosomiasis

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

Category

Researchers unravel mystery of how leukemia-causing mutations enable pre-leukemic stem cells to outperform their healthy counterparts

Nature: Stem cells – Dual response to Ras mutation

Dallas Observer: UT Southwestern researcher identifies gene that tricks the body into healing like a fetus

Nature: Fountain-of-youth gene unleashes healing power

Cellular regeneration discoveries seek to turn back the body’s clock

CRI researcher identifies new lung cancer therapeutic targets

Q&A with Woo-Ping Ge, Ph.D.

Sean Morrison and Corbin Meacham evaluate implications of new cancer stem cell data

CRI researchers review metabolic functions of glutamine

Sean Morrison, Ph.D., discusses stem cell research at Science Café

CRI researcher finds glucose connection to blood vessel formation

CRI researcher finds connection between excess fumarate and cancer

Inside CRI Newsletter

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