News

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help mutated cells …

Metabolism

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

Cancer Biology

June 11, 2025

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant…

December 9, 2024

Morrison receives E. Donnall Thomas Lecture & Prize from the American Society of Hematology

ASH Daily News feature story about Dr. Morrison’s award: The 2024 E. Donnall Thomas Awardee: Honoring …

November 20, 2024

Morrison, DeBerardinis named to ‘highly-cited’ researcher list for seventh consecutive year

Two Children’s Medical Center Research Institute at UT Southwestern (CRI) scientists have been named to Clarivate’s …

November 1, 2024

Mishra Lab discovers mitochondrial DNA mutations prevent metastasis in skin cancers

Research builds on prior CRI discovery about healthy mitochondrial metabolism being necessary for cancer spread Human …

Metabolism

October 24, 2024

Morrison Lab discovers ancient viral DNA activates blood cell production during pregnancy, after bleeding

Study published in Science shows humans co-opted retrotransposons to avoid anemia during pregnancy DALLAS – Oct. …

Regenerative Medicine

October 8, 2024

Garcia-Bermudez awarded NIH Director’s New Innovator Award

CRI researchers to study how metastatic cancers overcome lethal oxidative stress Javier Garcia-Bermudez, Ph.D., an assistant …

September 6, 2024

CRI awarded nearly $7M in research grants from CPRIT

August 14, 2024

DeBerardinis Lab discovers kidney cancers rely on mitochondrial metabolism to metastasize

DeBerardinis Lab researchers collaborated with UTSW surgeons to trace pathways used in kidney cancers from more …

Cancer Biology, Metabolism

July 11, 2024

Tumor growth fueled by nucleotide salvage

Hoxhaj Lab measures purine pathways across tissues and tumors, revealing crucial role of salvage pathway in …

Cancer Biology, Metabolism

June 19, 2024

PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

Summary: Somatic mutations in non-malignant tissues are selected for because they confer increased clonal fitness, however, …

Regenerative Medicine

June 18, 2024

Morrison to receive prestigious ASH E. Donnall Thomas Lecture and Prize

June 13, 2024

Metabolic inflexibility keeps damage at bay during liver regeneration

Mishra Lab pinpoints PDK4 enzyme that starves cells with mitochondrial damage (NEWS RELEASE) Liver cells have …

Metabolism, Regenerative Medicine

June 13, 2024

Electron transport chain inhibition increases cellular dependence on purine transport, salvage

Scientists have identified a new way to disrupt lung cancer growth in research from Children’s Medical …

Metabolism

Inside CRI Newsletter

Stay up-to-date with our latest discoveries and news by subscribing to our quarterly email newsletter.

Name

First Name Last Name

CAPTCHA

News

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

Category

Morrison receives E. Donnall Thomas Lecture & Prize from the American Society of Hematology

Morrison, DeBerardinis named to ‘highly-cited’ researcher list for seventh consecutive year

Mishra Lab discovers mitochondrial DNA mutations prevent metastasis in skin cancers

Morrison Lab discovers ancient viral DNA activates blood cell production during pregnancy, after bleeding

Garcia-Bermudez awarded NIH Director’s New Innovator Award

CRI awarded nearly $7M in research grants from CPRIT

DeBerardinis Lab discovers kidney cancers rely on mitochondrial metabolism to metastasize

Tumor growth fueled by nucleotide salvage

PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

Morrison to receive prestigious ASH E. Donnall Thomas Lecture and Prize

Metabolic inflexibility keeps damage at bay during liver regeneration

Electron transport chain inhibition increases cellular dependence on purine transport, salvage

Inside CRI Newsletter

About

Research

Shared Facilities

Training

News