News

June 11, 2025

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant protection from …

Cancer Biology

April 15, 2025

Hijai Regina Shin, Ph.D., named 2025 Searle Scholar

Newest investigator in Children’s Medical Center Research Institute at UT Southwestern recognized for innovative…

Cancer Biology, Metabolism

February 19, 2025

DeBerardinis Lab finds high glucose contribution to tricarboxylic acid cycle involved in predicting cancer spread

DALLAS – Feb. 19, 2025 – In localized non-small cell lung cancer (NSCLC), a…

July 11, 2024

Tumor growth fueled by nucleotide salvage

Hoxhaj Lab measures purine pathways across tissues and tumors, revealing crucial role of salvage pathway in …

Cancer Biology, Metabolism

June 19, 2024

PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

Summary: Somatic mutations in non-malignant tissues are selected for because they confer increased clonal fitness, however, …

Regenerative Medicine

June 18, 2024

Morrison to receive prestigious ASH E. Donnall Thomas Lecture and Prize

June 13, 2024

Metabolic inflexibility keeps damage at bay during liver regeneration

Mishra Lab pinpoints PDK4 enzyme that starves cells with mitochondrial damage (NEWS RELEASE) Liver cells have …

Metabolism, Regenerative Medicine

June 13, 2024

Electron transport chain inhibition increases cellular dependence on purine transport, salvage

Scientists have identified a new way to disrupt lung cancer growth in research from Children’s Medical …

Metabolism

June 3, 2024

Meet Dr. Hijai Regina Shin

Hijai Regina Shin, Ph.D., is the newest CRI faculty member, launching the Shin Lab in 2024 and …

May 1, 2024

Small cell lung cancer acquires cross-resistance due to extrachromosomal DNA amplification of MYC paralogs

Summary: Small cell lung cancer (SCLC) presents as a highly chemosensitive malignancy but acquires cross-resistance after …

Cancer Biology

March 1, 2024

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Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

Hijai Regina Shin, Ph.D., named 2025 Searle Scholar

DeBerardinis Lab finds high glucose contribution to tricarboxylic acid cycle involved in predicting cancer spread

Category

Tumor growth fueled by nucleotide salvage

PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer

Morrison to receive prestigious ASH E. Donnall Thomas Lecture and Prize

Metabolic inflexibility keeps damage at bay during liver regeneration

Electron transport chain inhibition increases cellular dependence on purine transport, salvage

Meet Dr. Hijai Regina Shin

Small cell lung cancer acquires cross-resistance due to extrachromosomal DNA amplification of MYC paralogs

Li receives 2024 ASH Scholar Award to research stem cells

Hoxhaj awarded Vilcek Prize for ‘Creative Promise in Biomedical Science’

DeBerardinis named NCI ‘2023 Outstanding Investigator’

Edward Owusu Kwarteng Awarded Minority Hematology Fellow Award from ASH

Divya Bezwada Receives the 2023 STAT Wunderkind Award

Inside CRI Newsletter

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