Cancer Biology May 19, 2026 Human cells can exchange genomic DNA that alters cell behavior Children’s Research Institute scientists discover that DNA transferred between cells can be inherited, remain…
Cancer Biology, Regenerative Medicine November 6, 2025 Location matters for liver cancer’s origins Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…
Cancer Biology June 11, 2025 Unique pathway tumors use to acquire antioxidant lipids uncovered CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant…
Cancer Biology, Metabolism February 19, 2025 High glucose contribution to tricarboxylic acid cycle involved in predicting cancer spread DALLAS – Feb. 19, 2025 – In localized non-small cell lung cancer (NSCLC), a…
Cancer Biology, Metabolism August 14, 2024 Kidney cancers rely on mitochondrial metabolism to metastasize DeBerardinis Lab researchers collaborated with UTSW surgeons to trace pathways used in kidney cancers…
Cancer Biology, Metabolism July 11, 2024 Tumor growth fueled by nucleotide salvage Hoxhaj Lab measures purine pathways across tissues and tumors, revealing crucial role of salvage…
Cancer Biology May 1, 2024 Small cell lung cancer acquires cross-resistance due to extrachromosomal DNA amplification of MYC paralogs Summary: Small cell lung cancer (SCLC) presents as a highly chemosensitive malignancy but acquires…
Cancer Biology April 12, 2023 The presence of extrachromosomal DNA can accelerate cancer formation Oncogene amplification on extrachromosomal DNA (ecDNA) drives the evolution of tumours and their resistance…
Cancer Biology October 12, 2022 Scientists discover a new mechanism for therapy resistance in acute leukemias New research has uncovered a previously unknown mechanism that explains why patients with acute…
Cancer Biology, Genetics August 18, 2022 Researchers identify new druggable therapeutic pathway in a deadly form of brain cancer Scientists in the McBrayer lab in Children’s Medical Center Research Institute at UT Southwestern…
