Relentless Discovery

Toward the Treatments of Tomorrow.

Children’s Medical Center Research Institute at UT Southwestern (CRI) is a joint venture of UT Southwestern Medical Center and Children’s Medical Center Dallas, the flagship hospital of Children’s Health.

Research Areas

Research in CRI is focused at the intersection of stem cells, cancer, and metabolism because we believe these areas hold uncommon opportunity for discoveries that could change the way we think about important scientific questions and yield new strategies for treating disease.

Genetic And Metabolic Disease Program

Scientists in CRI’s Genetic and Metabolic Disease Program are identifying the genetic basis of new human diseases and uncovering the mechanisms that link metabolic anomalies to tissue dysfunction. Understanding these mechanisms will lead to better treatments for diseases that involve perturbed metabolism.

Tissue Regeneration Program

Researchers in CRI’s Tissue Regeneration Program are identifying the cellular and genetic basis of tissue healing in a wide range of organs. Elucidation of these mechanisms will advance our ability to repair tissues damaged by age, disease, and trauma.

Cancer Biology

Cancer is a complex group of diseases characterized by uncontrolled cell proliferation and metastasis to other parts of the body. CRI researchers use a variety of approaches to identify the mechanisms that drive the formation and progression of several cancers in order to find new treatments.

About CRI

Commitment, vision, and a relentless determination to push the boundaries of knowledge.

CRI is home to over 150 researchers from all over the world working to answer fundamental scientific questions.

Inside CRI Newsletter

Stay up-to-date with our latest discoveries and news by subscribing to our quarterly email newsletter.