Research News Electron transport chain inhibition increases cellular dependence on purine transport, salvage All Research News >
Research News Electron transport chain inhibition increases cellular dependence on purine transport, salvage All Research News >
Cancer Biology, Metabolism July 11, 2024 Tumor growth fueled by nucleotide salvage Hoxhaj Lab measures purine pathways across tissues and tumors, revealing crucial role of salvage…
Metabolism, Regenerative Medicine June 13, 2024 Metabolic inflexibility keeps damage at bay during liver regeneration Mishra Lab pinpoints PDK4 enzyme that starves cells with mitochondrial damage (NEWS RELEASE) Liver…
Metabolism January 11, 2023 Lactate metabolism plays an important role in mitochondrial diseases Lactate, long considered to be a waste product of energy production, has been found…
Metabolism December 14, 2022 Scientists identify a molecular switch that speeds up muscle repair Recovery time for muscle sprains, strains, and other soft tissue injuries could be shortened…
Metabolism April 6, 2022 Researchers uncover unique metabolic needs during pregnancy Researchers in the DeBerardinis lab in CRI developed a new method to study metabolism…
Metabolism April 8, 2021 Mitochondrial NADP+ is essential for proline biosynthesis during cell growth Nicotinamide adenine dinucleotide phosphate (NADP+) is vital to produce NADPH, a principal supplier of…
Genetics, Metabolism April 30, 2019 New screening approach helps identify sources of rare genetic diseases in children Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) are using…
Metabolism June 28, 2018 Researchers discover new vulnerability in small cell lung cancer Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered…
Cancer Biology, Metabolism October 5, 2017 CRI study challenges long-standing concept in cancer metabolism Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate…
Cancer Biology, Metabolism June 20, 2017 DeBerardinis lab discovered an aggressive subset of lung cancer that relies on an unusual metabolic pathway to survive Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered…