News

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help mutated cells …

Metabolism

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

Cancer Biology

June 11, 2025

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant…

July 28, 2014

CRI scientists create new models to study liver cancer

Hepatocellular carcinoma (HCC) — the most common form of liver cancer — is the third leading …

June 20, 2014

CRI finds key to identifying, enriching mesenchymal stem cells

Children’s Medical Center Research Institute at UT Southwestern (CRI) has identified a biomarker that enables researchers …

Regenerative Medicine

May 22, 2014

CRI researchers identify key mechanism in metabolic pathway that fuels cancers

In a breakthrough discovery at the Children’s Medical Center Research Institute at UT Southwestern (CRI), a …

May 13, 2014

CRI makes surprising brain stem cell discovery

Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have made a surprising …

April 1, 2014

Children’s Research Institute launches Genetic and Metabolic Disease Program

Children’s Medical Center Research Institute at UT Southwestern has launched a Genetic and Metabolic Disease Program …

March 20, 2014

KERA: Sean Morrison Interview on Think

Sean Morrison, Ph.D., Director of the Children’s Research Institute, discusses what stem cells do, how and …

March 10, 2014

Researchers discover a method of measuring protein synthesis in adult stem cells

For the first time, researchers have shown that an essential biological process known as protein synthesis …

Regenerative Medicine

February 20, 2014

Sean Morrison delivers UTSW President’s Lecture

Sean Morrison, Ph.D., Director of the Children’s Research Institute, discusses his internationally recognized research as part …

January 22, 2014

Nature: Stem cells – Sex specificity in the blood

Males and females exhibit differences not only in reproductive organs, but also in sexually dimorphic tissues …

January 22, 2014

Scientists find estrogen promotes blood-forming stem cell function

Scientists have known for years that stem cells in male and female sexual organs are regulated …

Regenerative Medicine

January 15, 2014

Sean Morrison reviews HSC niche research

The potential for understanding how the biological setting that sustains blood-forming stem cells is involved in …

November 27, 2013

Researchers unravel mystery of how leukemia-causing mutations enable pre-leukemic stem cells to outperform their healthy counterparts

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI), the University of California …

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News

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

Category

CRI scientists create new models to study liver cancer

CRI finds key to identifying, enriching mesenchymal stem cells

CRI researchers identify key mechanism in metabolic pathway that fuels cancers

CRI makes surprising brain stem cell discovery

Children’s Research Institute launches Genetic and Metabolic Disease Program

KERA: Sean Morrison Interview on Think

Researchers discover a method of measuring protein synthesis in adult stem cells

Sean Morrison delivers UTSW President’s Lecture

Nature: Stem cells – Sex specificity in the blood

Scientists find estrogen promotes blood-forming stem cell function

Sean Morrison reviews HSC niche research

Researchers unravel mystery of how leukemia-causing mutations enable pre-leukemic stem cells to outperform their healthy counterparts

Inside CRI Newsletter

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