December 23, 2025 Loss of vitamin C synthesis protects animals from schistosomiasis Agathocleous Lab, collaborators discover vitamin C deficiency can benefit animals by depriving vitamin from parasitic worms …
November 6, 2025 Zhu Lab shows location matters for liver cancer’s origins Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…
Metabolism November 6, 2025 DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…
February 8, 2021 New vulnerability discovered in chemotherapy-resistant small cell lung cancer Researchers from the DeBerardinis lab have found a new metabolic liability in chemotherapy-resistant small cell lung …
February 1, 2021 Hao Zhu receives Mark Foundation for Cancer Research 2021 Emerging Leader Award Hao Zhu, M.D., an associate professor at CRI, was one of seven researchers selected by the …
January 4, 2021 Researchers uncover a potential treatment for an aggressive form of lung cancer Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new …
November 10, 2020 Sam McBrayer awarded grant from the V Foundation for Cancer Research Dr. Sam McBrayer, an assistant professor at CRI, received the V Foundation for Cancer Research’s V …
October 29, 2020 The possibility of immunotherapy for liver cancer prevention Chronic liver damage raises the risk of developing hepatocellular carcinoma (HCC) – the most common type …
October 19, 2020 Cancer metabolism researcher Ralph DeBerardinis elected to the National Academy of Medicine Ralph DeBerardinis, M.D., Ph.D., a professor at the Children’s Medical Center Research Institute at UT Southwestern …
September 23, 2020 Sean Morrison presented with Excellence in Postdoctoral Mentoring Award UT Southwestern’s Postdoctoral Association (PDA) has selected Dr. Sean Morrison, director of Children’s Medical Center Research …
September 7, 2020 Researchers show how mutations in DNA packaging machines cause cancer Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells …
August 19, 2020 Lymph protects metastasizing melanoma cells from ferroptosis For decades, physicians have known that many kinds of cancer cells often spread first to lymph … Cancer Biology
May 15, 2020 CRI graduate student Divya Bezwada receives 2020 Ida M. Green Award Divya Bezwada, a fourth year graduate student in the DeBerardinis lab at Children’s Medical Center Research …
April 27, 2020 Sean Morrison, Director of CRI elected to prestigious National Academy of Sciences Dr. Sean Morrison, Director of the Children’s Medical Center Research Institute at UT Southwestern (CRI) and Professor of …
April 17, 2020 CRI postdoctoral fellow Brandon Faubert receives NIH Pathway to Independence Award Brandon Faubert, Ph.D., a postdoctoral researcher in the DeBerardinis lab at CRI, was recently awarded a …