News

November 6, 2025

Zhu Lab shows location matters for liver cancer’s origins

Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help mutated cells …

Metabolism

November 6, 2025

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…

Cancer Biology

June 11, 2025

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

CRI researchers find cancer cells use sulfated glycosaminoglycans to draw in lipoproteins, gain antioxidant…

April 12, 2023

The presence of extrachromosomal DNA can accelerate cancer formation

Oncogene amplification on extrachromosomal DNA (ecDNA) drives the evolution of tumours and their resistance to treatment, …

Cancer Biology

April 10, 2023

Mutant clones in the liver may fight fatty liver disease

Somatic mutations in nonmalignant tissues accumulate with age and injury, but whether these mutations are adaptive …

Regenerative Medicine

March 1, 2023

Meet Dr. Shang Ma

Shang Ma, Ph.D., recently joined the institute as CRI’s newest faculty member and principal investigator. He …

January 11, 2023

Lactate metabolism plays an important role in mitochondrial diseases

Lactate, long considered to be a waste product of energy production, has been found to fuel …

Metabolism

December 14, 2022

Scientists identify a molecular switch that speeds up muscle repair

Recovery time for muscle sprains, strains, and other soft tissue injuries could be shortened thanks to …

Metabolism

November 29, 2022

New research challenges long-standing assumption of how liver cells produce energy

Within our cells, mitochondria are responsible for converting food into energy. This works by taking electrons …

October 21, 2022

Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries

New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) found that different skeletal stem …

Regenerative Medicine

October 12, 2022

Scientists discover a new mechanism for therapy resistance in acute leukemias

New research has uncovered a previously unknown mechanism that explains why patients with acute myeloid leukemia …

Cancer Biology

September 8, 2022

Xu lab trainee earns prestigious F30 Fellowship

Ever since he started working in a biomedical research lab and shadowing doctors in the hospital, …

August 18, 2022

Researchers identify new druggable therapeutic pathway in a deadly form of brain cancer

Scientists in the McBrayer lab in Children’s Medical Center Research Institute at UT Southwestern (CRI) have …

Cancer Biology, Genetics

June 22, 2022

CRI trainee earns National Cancer Institute Fellowship

Milan Savani, an M.D./Ph.D. student, is the latest CRI trainee to earn a Ruth L. Kirschstein …

June 20, 2022

CRI researcher earns 2022 Marshall Klaus Neonatal-Perinatal Research Award

Walter Chen, M.D., Ph.D., a postdoctoral fellow in the DeBerardinis lab in Children’s Medical Center Research Institute …

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News

Zhu Lab shows location matters for liver cancer’s origins

DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways

Garcia-Bermudez Lab uncovers unique pathway tumors use to acquire antioxidant lipids

Category

The presence of extrachromosomal DNA can accelerate cancer formation

Mutant clones in the liver may fight fatty liver disease

Meet Dr. Shang Ma

Lactate metabolism plays an important role in mitochondrial diseases

Scientists identify a molecular switch that speeds up muscle repair

New research challenges long-standing assumption of how liver cells produce energy

Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries

Scientists discover a new mechanism for therapy resistance in acute leukemias

Xu lab trainee earns prestigious F30 Fellowship

Researchers identify new druggable therapeutic pathway in a deadly form of brain cancer

CRI trainee earns National Cancer Institute Fellowship

CRI researcher earns 2022 Marshall Klaus Neonatal-Perinatal Research Award

Inside CRI Newsletter

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