Category: Discovery

Metabolism

January 11, 2023

Lactate metabolism plays an important role in mitochondrial diseases

Lactate, long considered to be a waste product of energy production, has been found…

Metabolism

December 14, 2022

Scientists identify a molecular switch that speeds up muscle repair

Recovery time for muscle sprains, strains, and other soft tissue injuries could be shortened…

Regenerative Medicine

October 21, 2022

Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries

New research from Children’s Medical Center Research Institute at UT Southwestern (CRI) found that different…

Cancer Biology

October 12, 2022

Scientists discover a new mechanism for therapy resistance in acute leukemias

New research has uncovered a previously unknown mechanism that explains why patients with acute…

Cancer Biology, Genetics

August 18, 2022

Researchers identify new druggable therapeutic pathway in a deadly form of brain cancer

Scientists in the McBrayer lab in Children’s Medical Center Research Institute at UT Southwestern…

Regenerative Medicine

May 22, 2022

Adiponectin receptors sustain haematopoietic stem cells throughout adulthood by protecting them from inflammation

How are haematopoietic stem cells (HSCs) protected from inflammation, which increases with age and…

Metabolism

April 6, 2022

Researchers uncover unique metabolic needs during pregnancy

Researchers in the DeBerardinis lab in CRI developed a new method to study metabolism…

Regenerative Medicine

February 16, 2022

New research finds muscle tissues absorb damaged stem cells

As we age, our muscle stem cells accumulate mitochondrial mutations that undermine the function…

Metabolism

April 8, 2021

Mitochondrial NADP+ is essential for proline biosynthesis during cell growth

Nicotinamide adenine dinucleotide phosphate (NADP+) is vital to produce NADPH, a principal supplier of…

Cancer Biology

April 8, 2021

Scientists discover “jumping” genes that can protect against blood cancers

New research has uncovered a surprising role for so-called “jumping” genes that are a…

Category: Discovery

Lactate metabolism plays an important role in mitochondrial diseases

Scientists identify a molecular switch that speeds up muscle repair

Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries

Scientists discover a new mechanism for therapy resistance in acute leukemias

Researchers identify new druggable therapeutic pathway in a deadly form of brain cancer

Adiponectin receptors sustain haematopoietic stem cells throughout adulthood by protecting them from inflammation

Researchers uncover unique metabolic needs during pregnancy

New research finds muscle tissues absorb damaged stem cells

Mitochondrial NADP+ is essential for proline biosynthesis during cell growth

Scientists discover “jumping” genes that can protect against blood cancers

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