December 23, 2025 Loss of vitamin C synthesis protects animals from schistosomiasis Agathocleous Lab, collaborators discover vitamin C deficiency can benefit animals by depriving vitamin from parasitic worms …
November 6, 2025 Zhu Lab shows location matters for liver cancer’s origins Hepatocellular carcinoma arises primarily in zone 3 due to glutathione transferase genes that help…
Metabolism November 6, 2025 DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways NUDT5 suppresses de novo purine biosynthesis through PPAT interaction, affects thiopurine sensitivity The protein…
November 8, 2021 Ralph DeBerardinis receives 2021 Paul Marks Prize for Cancer Research Ralph DeBerardinis, M.D., Ph.D., a Professor at Children’s Medical Center Research Institute at UT Southwestern (CRI), …
August 10, 2021 Metabolic differences in cancer cells may be driven by cell of origin The metabolic differences observed between cancer and normal tissue are often thought to reflect the reprogramming …
July 20, 2021 Meet Dr. Sihan Wu Dr. Sihan Wu recently became the institute’s tenth faculty member and principal investigator. He earned his …
July 7, 2021 Dr. Corbitt selected to be Dedman Scholar Natasha Corbitt, M.D., Ph.D., a researcher in the Zhu lab at CRI and a pediatric surgeon …
June 15, 2021 CRI clinical fellow earns ASCO’s Young Investigator Award to improve radiotherapy delivery Faith Zhang, M.D., Ph.D., a clinical fellow in radiation oncology in the DeBerardinis lab, has been …
June 7, 2021 CRI grad student awarded an American Heart Association Predoctoral Fellowship Giovanni Botten, an M.D./Ph.D. student in the Xu lab, was awarded an American Heart Association (AHA) …
April 13, 2021 CRI trainee receives National Research Service F30 Award to study HCC Sherwin Kelekar, an M.D./Ph.D. student in the DeBerardinis lab at CRI, was awarded a Ruth L. …
April 8, 2021 Mitochondrial NADP+ is essential for proline biosynthesis during cell growth Nicotinamide adenine dinucleotide phosphate (NADP+) is vital to produce NADPH, a principal supplier of reducing power … Metabolism
April 8, 2021 Scientists discover “jumping” genes that can protect against blood cancers New research has uncovered a surprising role for so-called “jumping” genes that are a source of … Cancer Biology
March 30, 2021 Meet Dr. Ben Ohlstein Children’s Medical Center Research Institute at UT Southwestern (CRI) recently recruited Dr. Ben Ohlstein to become …
February 25, 2021 Scientists identify cells responsible for liver tissue maintenance and regeneration While the amazing regenerative power of the liver has been known since ancient times, the cells … Regenerative Medicine
February 24, 2021 Researchers identify mechanism by which exercise strengthens bones and immunity Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized … Regenerative Medicine